Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221891 | 0.80 | SLC18A3 (0.41) | SLC18A3MEN1KMT2AATMALPL | |
| SCHEMBL11186239 | 0.71 | MEN1 (0.61) | MEN1KMT2AATMALPLALPI | |
| SCHEMBL9953363 | 0.70 | KMT2A (0.40) | SLC18A3MEN1KMT2AATMALPL | |
| SCHEMBL7695527 | 0.69 | NPC1 (0.40) | MEN1KMT2AATMALPLALPI | |
| SCHEMBL9207860 | 0.68 | TOP2A (0.66) | MEN1KMT2ACYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL280518 | 0.67 | MEN1 (0.40) | SLC18A3MEN1KMT2AATMALPL | |
| SCHEMBL28801759 | 0.66 | MEN1 (0.54) | MEN1KMT2AATMALPLALPI | |
| SCHEMBL11152674 | 0.65 | ALPL (0.38) | MEN1KMT2AATMALPLALPI | |
| SCHEMBL27542583 | 0.64 | MAOB (0.42) | MEN1KMT2AATMALDH1A1 | |
| SCHEMBL11215454 | 0.63 | SMN1; SMN2 (0.40) | MEN1KMT2AATMALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010852-A1 | Process for the preparation of tetramisole | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | claimed |
| EP-0010852-B1 | PROCESS FOR THE PREPARATION OF TETRAMISOLE | AMERICAN CYANAMID COMPANY (US) | 1982-09-08 | — | — | EP | disclosed |
| US-4316038-A | 1-(2-Methoxyethyl)-2-methyl-4-phenyl-2-imidazoline | AMERICAN CYANAMID COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4245102-A | Processes for the preparation of tetramisole | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| EP-0010852-A1 | Process for the preparation of tetramisole | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | disclosed |