Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225538 | 1.00 | CNKSR1 (0.49) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL11210430 | 0.91 | CNKSR1 (0.44) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL11210433 | 0.91 | CNKSR1 (0.44) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL1562282 | 0.85 | MAOB (0.48) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL1562279 | 0.85 | MAOB (0.48) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL11216858 | 0.82 | CYP3A4 (0.50) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL11216857 | 0.82 | CYP3A4 (0.50) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| SCHEMBL18069259 | 0.82 | ALDH1A1 (0.49) | CNKSR1CYP3A4MAOBDPP4TTR | |
| Hydrochloric Acid SCHEMBL11215040 | 0.81 | CNKSR1 (0.49) | CNKSR1CYP3A4MAOBALOX5DPP4 | |
| Hydrochloric Acid SCHEMBL11215035 | 0.81 | CNKSR1 (0.49) | CNKSR1CYP3A4MAOBALOX5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |