Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978827 | 1.00 | FAAH (0.48) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL10705949 | 1.00 | FAAH (0.48) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL20399557 | 1.00 | FAAH (0.48) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL28662838 | 1.00 | FAAH (0.48) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL8914703 | 0.98 | — | — | |
| SCHEMBL8962977 | 0.90 | — | — | |
| SCHEMBL6159056 | 0.87 | HDAC3 (0.55) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL5909431 | 0.87 | HDAC3 (0.55) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL5909483 | 0.87 | HDAC3 (0.55) | FAAHLMNAHDAC1HDAC8HDAC3 | |
| SCHEMBL12333287 | 0.87 | HDAC3 (0.55) | FAAHLMNAHDAC1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320134-A | HYPOTENSIVE, ANTIASTHMATIC AND ANTIINFLAMMATORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-16 | — | — | US | disclosed |