⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662838 | 0.98 | FAAH (0.48) | — | |
| SCHEMBL10705949 | 0.98 | FAAH (0.48) | — | |
| SCHEMBL11225685 | 0.98 | FAAH (0.48) | — | |
| SCHEMBL20399557 | 0.98 | FAAH (0.48) | — | |
| SCHEMBL18978827 | 0.98 | FAAH (0.48) | — | |
| SCHEMBL8962977 | 0.92 | — | — | |
| SCHEMBL7753090 | 0.87 | LMNA (0.57) | — | |
| SCHEMBL5909483 | 0.84 | HDAC3 (0.55) | — | |
| SCHEMBL12333287 | 0.84 | HDAC3 (0.55) | — | |
| SCHEMBL6159056 | 0.84 | HDAC3 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607960-A | Indole derivatives as 5-HT1-like agonists for use in migraine | PFIZER INC. (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0695301-B1 | INDOLE DERIVATIVES AS 5-HT1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LTD (GB) | 1996-10-30 | — | — | EP | disclosed |
| CN-1121348-A | Indole derivatives as 5-H1-like agonists for use in migraine | PFIZER RES & DEV (IE) | 1996-04-24 | — | — | CN | disclosed |
| EP-0695301-A1 | INDOLE DERIVATIVES AS 5-H1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LTD (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024127-A1 | INDOLE DERIVATIVES AS 5-H1-LIKE AGONISTS FOR USE IN MIGRAINE | PFIZER LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| EP-0262404-B1 | GLUCOSYLMORANOLINE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4855415-A | Glucosylmoranoline derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0262404-A1 | Glucosylmoranoline derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |