Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11227227 | 0.99 | HTR6 (0.38) | HTR6KDM4ETDP1KMT2ASIGMAR1 | |
| SCHEMBL11386590 | 0.89 | HTR6 (0.41) | HTR6KDM4ETDP1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL11240193 | 0.89 | HTR6 (0.40) | HTR6KDM4ETDP1KMT2ASIGMAR1 | |
| SCHEMBL11246816 | 0.88 | HTR6 (0.35) | HTR6KDM4ETDP1KMT2ASIGMAR1 | |
| SCHEMBL11362472 | 0.86 | HTR6 (0.41) | HTR6KDM4ETDP1KMT2ALOXL2 | |
| SCHEMBL11249316 | 0.85 | HTR6 (0.56) | HTR6KDM4ETDP1 | |
| SCHEMBL11227272 | 0.84 | KDM4E (0.38) | HTR6KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL11724290 | 0.77 | ABCB1 (0.41) | KDM4EKMT2ASIGMAR1MEN1ALDH1A1 | |
| SCHEMBL11218517 | 0.76 | ALDH1A1 (0.35) | HTR6KDM4ESIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11367098 | 0.76 | HTR6 (0.44) | HTR6KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256890-A | ADRENERGIC BLOCKING AGENTS | OTSUKAPHARMACEUTICAL CO., LTD. (JP) | 1981-03-17 | — | — | US | claimed |
| US-4309432-A | TOPICAL ADMINISTRATION | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |