SCHEMBL11225849

SCHEMBL11225849

OCC(S)c1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.44
ALOX15 P16050 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
TBXA2R P21731 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
ADRA1A P35348 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10594951 0.78 MEN1 (0.38) ALOX15TDP1CYP3A4MAPTHIF1A
SCHEMBL6401479 0.77 TRPA1 (0.45) LMNACYP2D6TAAR1TSHRKDM4E
SCHEMBL1408602 0.77 TRPA1 (0.45) LMNACYP2D6TAAR1TSHRKDM4E
SCHEMBL19632871 0.77 TRPA1 (0.45) LMNACYP2D6TAAR1TSHRKDM4E
SCHEMBL1268287 0.74 ESR1 (0.48) ESR1ALOX15TDP1LMNACYP3A4
SCHEMBL989866 0.73 CA2 (0.43) ESR1ALOX15TDP1LMNACYP3A4
SCHEMBL300321 0.73 ESR1 (0.39) ESR1ALOX15TDP1LMNACYP3A4
SCHEMBL477410 0.73 ESR1 (0.39) ESR1ALOX15TDP1LMNACYP3A4
SCHEMBL4002669 0.73 ESR1 (0.52) ESR1ALOX15TDP1LMNACYP3A4
SCHEMBL7895108 0.72 TAAR1 (0.62) ESR1ALOX15TDP1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 US disclosed