Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220704 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL3380493 | 0.83 | GAA (0.53) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL20210942 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL7594139 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL7519140 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL29171363 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL130085 | 0.77 | GAA (0.49) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL1979095 | 0.76 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7594094 | 0.75 | GAA (0.51) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL11223687 | 0.74 | GAA (0.47) | ALDH1A1GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011843-B1 | DEVELOPING COMPONENTS FOR HAIR OXYDATION DYES, THEIR PREPARATION AND HAIR DYES CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0011843-A2 | Developing components for hair oxydation dyes, their preparation and hair dyes containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1980-06-11 | — | — | EP | disclosed |