SCHEMBL130085

SCHEMBL130085

Nc1ccc(N)c(OCC(O)COc2cc(N)ccc2N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.49
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 6/20 0.40
MAPT P10636 5/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
POLB P06746 2/20 0.40
MAPK1 P28482 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 4/20 0.38
CYP1A2 P05177 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 3/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7594094 0.98 GAA (0.51) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL10494910 0.91 ALOX15 (0.47) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL28288200 0.91 CYP1A2 (0.47) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL7594139 0.90 ALDH1A1 (0.50) GAAALDH1A1KDM4EMAPTMEN1
Hydrochloric Acid SCHEMBL10494922 0.90 ALOX15 (0.50) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL20210942 0.85 ALDH1A1 (0.54) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL6252152 0.85 ALDH1A1 (0.49) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL11151986 0.85 GAA (0.53) GAAALDH1A1KDM4EMAPTMEN1
Hydrochloric Acid SCHEMBL11155467 0.81 GAA (0.54) GAAALDH1A1KDM4EMAPTMEN1
SCHEMBL11220704 0.81 ALDH1A1 (0.58) GAAALDH1A1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 797 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-12-31 US claimed
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-08 US claimed
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-01 US claimed
US-12097274-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-09-24 US claimed
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product HENKEL AG & CO. KGAA (DE) 2024-08-27 US claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2023-10-26 US claimed
US-20230310296-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-10-05 US claimed
WO-2023163906-A1 OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS HENKEL AG & CO. KGAA (DE) 2023-08-31 WO claimed
US-20230270647-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-08-31 US claimed
US-9445977-B2 Multi-tonal one step dyeing HENKEL AG & CO. KGAA (DE) 2016-09-20 US claimed
US-9402795-B2 Multi-tonal one-step dyes HENKEL AG & CO. KGAA (DE) 2016-08-02 US claimed
US-20150366773-A1 MULTI-TONAL ONE STEP DYEING HENKEL AG & CO. KGAA (DE) 2015-12-24 US claimed
US-20150366772-A1 MULTI-TONAL ONE-STEP DYES HENKEL AG & CO. KGAA (DE) 2015-12-24 US claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1759735-B1 Method of selectively dyeing portions of hair HENKEL KGAA (DE) 2007-12-05 EP claimed
EP-1776984-A2 Method for extending the recoloring cycles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-04-25 EP claimed
EP-1759735-A1 Method of selectively dyeing portions of hair Henkel Kommanditgesellschaft auf Aktien (DE) 2007-03-07 EP claimed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 US claimed
WO-2002096382-A1 DEVELOPER COMPONENTS FOR OXIDATION HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-12-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 GAA 4422/4885ALDH1A1 40/4885KDM4E 1626/4885
US-20230338267-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT OGG1, ALPG, OAT GAA 478/4885ALDH1A1 1913/4885KDM4E 1379/4885
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections KRT18, CUTA, PLOD2 GAA 4537/4885ALDH1A1 159/4885KDM4E 2132/4885
US-20230270647-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations KRT18, ALDH5A1, COX5A GAA 4289/4885ALDH1A1 28/4885KDM4E 1573/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO GAA 2405/4885ALDH1A1 111/4885KDM4E 1526/4885
US-12070517-B2 Thickened alkalyzation component for oxidative hair dyeing product OGG1, ALPG, OAT GAA 498/4885ALDH1A1 1825/4885KDM4E 1333/4885
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 GAA 3966/4885ALDH1A1 26/4885KDM4E 1445/4885
US-12097274-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, COX5A GAA 4289/4885ALDH1A1 28/4885KDM4E 1573/4885
US-20230310296-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations KRT18, ALDH5A1, ALDH2 GAA 4422/4885ALDH1A1 40/4885KDM4E 1626/4885
US-12178897-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, COX5A GAA 4387/4885ALDH1A1 37/4885KDM4E 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.