SCHEMBL11225975

SCHEMBL11225975

Nc1ccccc1S(=O)(=O)Nc1nc(Cl)nc(Cl)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKBIA P25963 2/20 0.49
RELA Q04206 2/20 0.49
SLC40A1 Q9NP59 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 2/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 3/20 0.46
CA9 Q16790 5/20 0.45
CA12 O43570 4/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA14 Q9ULX7 3/20 0.43
CYP2C9 P11712 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8864437 0.82 NFKBIA (0.51) NFKBIARELASLC40A1MEN1KMT2A
SCHEMBL3644476 0.79 TSHR (0.62) NFKBIARELASLC40A1MEN1KMT2A
SCHEMBL3837982 0.78 NFKBIA (0.60) NFKBIARELASLC40A1MEN1KMT2A
SCHEMBL10888517 0.77 NFKBIA (0.58) NFKBIARELASLC40A1MEN1KMT2A
SCHEMBL10643363 0.76 TSHR (0.62) SLC40A1MEN1KMT2AGAAPKM
SCHEMBL10636943 0.74 SLC40A1 (0.55) SLC40A1MEN1KMT2ATDP1LMNA
SCHEMBL11225968 0.73 ALDH1A1 (0.64) MEN1KMT2ATDP1LMNACA9
SCHEMBL641594 0.73 CES1 (0.55) MEN1KMT2ATDP1GAACA9
SCHEMBL11269034 0.73 SLC40A1 (0.49) NFKBIARELASLC40A1MEN1KMT2A
SCHEMBL2986277 0.73 NPSR1 (0.65) NFKBIARELASLC40A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4355099-A Composite photographic material having a thin flexable support and a reflecting layer CIBA-GEIGY AG (CH) 1982-10-19 US disclosed
US-4296198-A Photographic process using a thin flexuous layer and reflective layer CIBA-GEIGY AG (CH) 1981-10-20 US disclosed