Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.55 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423429 | 1.00 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11423431 | 1.00 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11444166 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11519106 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11061430 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11841581 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11215786 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811911 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811905 | 0.94 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11825336 | 0.93 | PTGS1 (0.60) | PTGS1L3MBTL1TDP1CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000285-B1 | 7-ACYLAMINO-3-((3-(CARBOXYMETHYL) THIO-1 H-1,2,4-TRIAZOL-5-YL) THIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1982-02-17 | — | — | EP | disclosed |
| EP-0000100-B1 | 7-ACYLAMINO-3-(1-(2-SULFAMOYLAMINOETHYL)-TETRAZOL-5-YLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACIDS, A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1982-02-03 | — | — | EP | disclosed |
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4220644-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4210587-A | 7-Acylamino-3-[1-[2-(carboxymethylamino)ethyl]tetrazol-5-ylthio methyl]-3-cephem-4-carboxylic acids | SMITHKLINE CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4174324-A | 3-(Carboxymethyl)thio-1H-1,2,4-triazol-5-thione | SMITHKLINE CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| US-4174323-A | BACTERICIDE, CEPHALOSPORIN INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| US-4159373-A | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4147701-A | BACTERICIDES, 1-CARBOXYMETHYLTHIOETHYLTETRAZOLE-5-THIOL | SMITHKLINE CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4144241-A | CEPHALOSPORIN MODIFIERS | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4103008-A | ANTIBIOTICS | TOSHIYASU ISHIMARU | 1978-07-25 | — | — | US | disclosed |
| US-4093723-A | ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4083975-A | BACTERICIDES, SEMI-SYNTHETIC CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-4079134-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4064242-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |
| US-4060610-A | Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections | SMITHKLINE CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4057631-A | CEPHALOSPORINS, BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |
| US-4048311-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-RE29164-E | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3989694-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |