Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811905 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11061430 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811911 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11215786 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11519106 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11841581 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL32670889 | 0.94 | CTDSP1 (0.70) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11423431 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11225982 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11423429 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013650-A | PROCESS FOR THE MANUFACTURE OF 3-METHYLENE-CEPHAM COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | claimed |
| US-4211703-A | CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1980-07-08 | — | — | US | disclosed |
| US-4189573-A | CHEMICAL INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |
| US-4112086-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4101656-A | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4013650-A | PROCESS FOR THE MANUFACTURE OF 3-METHYLENE-CEPHAM COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |