Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061430 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11444166 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL10811911 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11215786 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11519106 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11841581 | 1.00 | PTGS1 (0.71) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL32670889 | 0.94 | CTDSP1 (0.70) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11423431 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11225982 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT | |
| SCHEMBL11423429 | 0.94 | PTGS1 (0.63) | PTGS1L3MBTL1TDP1CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277023-A1 | ANTIBIOTIC CONJUGATES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-09-09 | — | — | US | disclosed |
| US-4668781-A | Ceph-3-one compounds and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| US-4591642-A | Cephem and cepham derivatives | CIBA-GEIGY CORPORATION (US) | 1986-05-27 | — | — | US | disclosed |
| US-4477658-A | Process for the preparation of cepham and cephem compounds | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4405778-A | Process for preparing cephalosporin ethers | CIBA-GEIGY CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4389524-A | Cepham compounds | CIBA-GEIGY CORPORATION (US) | 1983-06-21 | — | — | US | disclosed |
| US-4178288-A | Sulfaminoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4171368-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171362-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171433-A | 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4066761-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4064242-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |
| US-4060610-A | Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections | SMITHKLINE CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |
| US-4059591-A | Ureidoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4048311-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4025626-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3989694-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3968226-A | 3-Heterocyclic thiomethylcephalosporins as antibacterial agents | SMITHKLINE CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277023-A1 | ANTIBIOTIC CONJUGATES | DDOST, STT3B, DAD1 | PTGS1 2451/4885L3MBTL1 2502/4885TDP1 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.