SCHEMBL11226258

SCHEMBL11226258

CCn1[c]ncc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
IDO1 P14902 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
BRD4 O60885 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 1/20 0.34
NLRP3 Q96P20 1/20 0.34
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADORA1 P30542 1/20 0.33
RAC2 P15153 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28941634 0.86 ALDH1A1 (0.41) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL2711037 0.75 CYP1A2 (0.48) ALDH1A1CYP3A4CYP1A2CYP2D6MAPT
SCHEMBL7381151 0.74 ALDH1A1 (0.43) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL27654015 0.69 ALDH1A1 (0.40) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL16193332 0.67 KDM4E (0.59) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL794659 0.67 TSHR (0.43) KDM4EALDH1A1HPGDKMT2AHSD17B10
SCHEMBL8848068 0.66 LMNA (0.41) KDM4EALDH1A1CYP1A2MAPTKMT2A
SCHEMBL24011415 0.64 HDAC1 (0.48) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL1501902 0.64 CYP11B1 (0.66) IDO1CYP11B1CYP11B2
SCHEMBL19419968 0.63 KDM4E (0.47) KDM4EALDH1A1CYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4326065-A PLASTICS, VARNISHES, POLYESTERS EASTMAN KODAK COMPANY (US) 1982-04-20 US disclosed
US-4251433-A BENZOTRIAZOLE DERIVATIVES; FOR POLYMERS EASTMAN KODAK COMPANY (US) 1981-02-17 US disclosed
US-4236013-A ADDITIVES FOR POLYMERS EASTMAN KODAK COMPANY (US) 1980-11-25 US disclosed
US-4172081-A Benzotriazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-10-23 US disclosed
US-4162254-A Benzoxazole ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-24 US disclosed
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4137235-A ULTRAVIOLET STABILIZERS IN POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1979-01-30 US disclosed
US-4116928-A Heterocylic ester, ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4096115-A Ultraviolet light stabilized polymers EASTMAN KODAK COMPANY (US) 1978-06-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed