Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168892 | 0.75 | TBXAS1 (0.48) | TBXAS1 | |
| SCHEMBL11168702 | 0.74 | TBXAS1 (0.44) | TBXAS1 | |
| SCHEMBL11167375 | 0.72 | TBXAS1 (0.47) | TBXAS1 | |
| SCHEMBL5146760 | 0.72 | TBXAS1 (0.47) | TBXAS1 | |
| SCHEMBL11070611 | 0.71 | TBXAS1 (0.63) | CSNK1A1CSNK1DCLK2CSNK1G1TBXAS1 | |
| SCHEMBL11172992 | 0.71 | CYP11B1 (0.48) | TBXAS1 | |
| SCHEMBL10532359 | 0.71 | TBXAS1 (0.48) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL11005148 | 0.70 | TBXAS1 (0.61) | CSNK1A1CSNK1DCLK2CSNK1G1TBXAS1 | |
| Hydrochloric Acid SCHEMBL11097478 | 0.70 | TBXAS1 (0.48) | TBXAS1 | |
| SCHEMBL6922496 | 0.67 | PPARG (0.50) | CYP2C9EGFRALDH1A1CYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080154-A2 | N-substituted 2-pyridyl indoles, process for their preparation, pharmaceutical compositions containing them, and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-06-01 | — | — | EP | disclosed |