Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845648 | 0.80 | SLC6A4 (0.45) | SLC6A2SLC6A3MAPTKDM4ECYP3A4 | |
| SCHEMBL10907042 | 0.74 | ADORA3 (0.52) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL14357615 | 0.73 | ESR1 (0.49) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL4813960 | 0.71 | KMT2A (0.60) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL13144066 | 0.71 | MAPT (0.55) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL1256640 | 0.70 | ELANE (0.51) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL22582661 | 0.70 | ADORA3 (0.45) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL4808279 | 0.70 | MAPT (0.51) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL13242034 | 0.70 | LMNA (0.62) | ESR1PGRCHRM2ADORA3AR | |
| SCHEMBL15179068 | 0.70 | MAPT (0.54) | ESR1PGRCHRM2ADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310523-A | Combined antiestrogens and antigonadotropically effective antiandrogens for the prophylaxis and therapy of hyperplasia of the prostate | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | claimed |
| US-9011913-B2 | Use of functionalized magnetic nanoparticles in cancer detection and treatment | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-21 | — | — | US | disclosed |