Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858914 | 0.83 | HTR1D (0.46) | DRD2TDP1ALDH1A1KMT2AHTR1B | |
| SCHEMBL11225424 | 0.82 | HTR1B (0.43) | DRD2KDM4ETDP1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11230318 | 0.81 | HTR1B (0.42) | DRD2KDM4ETDP1ADRB2ADRB1 | |
| SCHEMBL11572052 | 0.81 | DRD2 (0.57) | DRD2KDM4ETDP1ADRB2ADRB1 | |
| SCHEMBL11864174 | 0.80 | HTR1B (0.43) | DRD2KDM4ETDP1ADRB2ADRB1 | |
| SCHEMBL11221461 | 0.79 | ADRB2 (0.54) | DRD2ADRB2ADRB1 | |
| SCHEMBL11872997 | 0.78 | DRD2 (0.40) | DRD2ADRB2ADRB1KMT2AHTR1B | |
| SCHEMBL10064553 | 0.75 | MCHR1 (0.48) | DRD2TDP1HTR1BMCHR1 | |
| SCHEMBL11873001 | 0.75 | KDM4E (0.38) | DRD2KDM4EALDH1A1KMT2AHTR1B | |
| SCHEMBL9820774 | 0.74 | MCHR1 (0.49) | TDP1KMT2AMEN1HTR1BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953456-A | ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-4309432-A | TOPICAL ADMINISTRATION | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| US-3953456-A | ADRENERGIC BLOCKING AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |