Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123312 | 0.92 | GPR34 (0.59) | PPARGGPR34GPR132PTPN1 | |
| SCHEMBL1123055 | 0.85 | GAA (0.80) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1122724 | 0.83 | KMT2A (0.56) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1123233 | 0.83 | GAA (0.54) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL27658917 | 0.83 | GAA (0.68) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1122871 | 0.83 | GAA (0.68) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1122925 | 0.82 | GAA (0.75) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1122834 | 0.82 | GAA (0.75) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL1123370 | 0.81 | GAA (0.73) | GAARAB9ALNPEPERAP2LMNA | |
| SCHEMBL6030161 | 0.81 | GAA (0.77) | GAARAB9ALNPEPERAP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |