Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | YAP1 | P46937 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122834 | 0.99 | GAA (0.75) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL1123055 | 0.95 | GAA (0.80) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL1122925 | 0.92 | GAA (0.75) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL1123370 | 0.91 | GAA (0.73) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL6029421 | 0.91 | GAA (0.67) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL1123028 | 0.89 | GPR132 (0.71) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL6029880 | 0.89 | GPR132 (0.73) | GAARAB9APPARGGPR132PTPN1 | |
| SCHEMBL1123382 | 0.89 | GAA (0.71) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL1123147 | 0.89 | GAA (0.71) | GAARAB9APPARGGPR132ERAP2 | |
| SCHEMBL27638047 | 0.89 | RAB9A (0.74) | GAARAB9APPARGGPR132ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247260-A1 | Bis (hetero) aryl carboxamide derivatives for use as PG12 antagonists | BAYER HEALTHCARE AG (DE) | 2006-11-02 | — | — | US | disclosed |
| EP-1594846-A1 | BIS(HETERO)ARYL CARBOXAMIDE DERIVATIVES FOR USE AS PGI2 ANTAGONISTS | Bayer HealthCare AG (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069805-A1 | BIS(HETERO)ARYL CARBOXAMIDE DERIVATIVES FOR USE AS PGI2 ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247260-A1 | Bis (hetero) aryl carboxamide derivatives for use as PG12 antagonists | HRH2, BPHL, HRH1 | GAA 3163/4885RAB9A 3403/4885PPARG 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.