Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159618 | 0.91 | POLB (0.56) | POLBCCR1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL6437249 | 0.88 | POLB (0.62) | POLBCCR1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL17294673 | 0.86 | SOS1 (0.48) | POLBSOS1EPHX1TSHR | |
| SCHEMBL17294658 | 0.86 | SOS1 (0.48) | POLBSOS1EPHX1TSHR | |
| SCHEMBL17294675 | 0.86 | SOS1 (0.48) | POLBSOS1EPHX1TSHR | |
| SCHEMBL6009184 | 0.84 | GRM7 (0.64) | SOS1EPHX1TSHR | |
| SCHEMBL14050745 | 0.83 | CCR1 (0.68) | POLBCCR1ALDH1A1EPHX1TSHR | |
| SCHEMBL8365416 | 0.82 | HTR1E (0.61) | TSHRMAPTC3AR1 | |
| SCHEMBL24671897 | 0.82 | POLB (0.53) | POLBCCR1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL17294653 | 0.81 | TSHR (0.56) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361562-A | CARDIOTONIC, ANTIARRHYTHMIC AND ADRENOCEPTOR BLOCKING AGENTS | SANDOZ LTD. (CH) | 1982-11-30 | — | — | US | disclosed |