Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219246 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL11230380 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL11232200 | 0.98 | PRSS1 (0.47) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL11225382 | 0.95 | DGKA (0.46) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL11223635 | 0.89 | DGKA (0.52) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL11221476 | 0.87 | TSHR (0.46) | PRSS1PRSS2PRSS3CES2TSHR | |
| SCHEMBL21318391 | 0.85 | DGKA (0.47) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL16754908 | 0.85 | DGKA (0.55) | PRSS1PRSS2PRSS3DGKADNM1 | |
| SCHEMBL21052530 | 0.84 | PRSS1 (0.38) | PRSS1PRSS2PRSS3DGKACES2 | |
| SCHEMBL21052534 | 0.84 | PRSS1 (0.38) | PRSS1PRSS2PRSS3DGKACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |