Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21318391 | 0.96 | DGKA (0.47) | DGKAPRSS1PRSS2PRSS3THRB | |
| SCHEMBL1791414 | 0.92 | ADRA2A (0.43) | DGKAPRSS1PRSS2PRSS3THRB | |
| SCHEMBL11232200 | 0.91 | PRSS1 (0.47) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11225382 | 0.91 | DGKA (0.46) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11219246 | 0.89 | PRSS1 (0.50) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11226564 | 0.89 | PRSS1 (0.50) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11230380 | 0.89 | PRSS1 (0.50) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL6523998 | 0.85 | ADRA2A (0.38) | DGKATHRBPAMTSHRALDH1A1 | |
| SCHEMBL20335287 | 0.82 | THRB (0.46) | DGKATHRBTSHRALDH1A1BLM | |
| SCHEMBL17169822 | 0.81 | PAM (0.50) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |