Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226724 | 1.00 | MEN1 (0.41) | MEN1KMT2ACYP19A1EGLN3CYP1A2 | |
| SCHEMBL11235993 | 0.76 | CYP19A1 (0.40) | MEN1KMT2ACYP19A1EGLN3CYP1A2 | |
| SCHEMBL11235997 | 0.76 | CYP19A1 (0.40) | MEN1KMT2ACYP19A1EGLN3CYP1A2 | |
| SCHEMBL3232702 | 0.74 | MEN1 (0.50) | MEN1KMT2AEGLN3CYP1A2CYP3A4 | |
| SCHEMBL11237990 | 0.74 | KMT2A (0.41) | MEN1KMT2AEGLN3CYP1A2CYP3A4 | |
| SCHEMBL13054779 | 0.72 | MAPT (0.49) | CYP19A1EGLN3MAPTFDPS | |
| SCHEMBL5412057 | 0.72 | MAPT (0.49) | CYP19A1EGLN3MAPTFDPS | |
| SCHEMBL11248685 | 0.71 | FDPS (0.39) | FDPS | |
| SCHEMBL11238618 | 0.71 | FDPS (0.38) | MEN1KMT2ACYP19A1EGLN3CYP1A2 | |
| SCHEMBL11248682 | 0.71 | FDPS (0.39) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359469-A | Combating pests with N-sulphenylated oxime-carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| EP-0005780-A1 | N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |