Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248682 | 1.00 | FDPS (0.39) | FDPSTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL11225805 | 0.76 | NOS1 (0.41) | FDPSTSHRNOS1BRD4NOS3 | |
| SCHEMBL11225802 | 0.76 | NOS1 (0.41) | FDPSTSHRNOS1BRD4NOS3 | |
| SCHEMBL13101056 | 0.74 | FDPS (0.44) | FDPSTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL11245279 | 0.74 | NLRP3 (0.34) | FDPSTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL11226724 | 0.71 | MEN1 (0.41) | FDPS | |
| SCHEMBL11226720 | 0.71 | MEN1 (0.41) | FDPS | |
| SCHEMBL11235939 | 0.71 | FDPS (0.35) | FDPSTSHRNOS1BRD4NOS3 | |
| SCHEMBL11235953 | 0.71 | FDPS (0.35) | FDPSTSHRNOS1BRD4NOS3 | |
| SCHEMBL18231656 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359469-A | Combating pests with N-sulphenylated oxime-carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| EP-0005780-A1 | N,N'-asymmetrically substituted thio-bis-amines, process for their preparation and their use as insecticides, acaricides and nematocides | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |