Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.59 |
| ▸ | TUBB | P07437 | 7/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.59 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826464 | 0.85 | ALDH1A1 (0.85) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL826463 | 0.85 | ALDH1A1 (0.85) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL1122446 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1324945 | 0.82 | EGFR (0.58) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL1324862 | 0.82 | EGFR (0.58) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL1324870 | 0.82 | EGFR (0.58) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL826538 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAEGFRPTGES2KDM4E | |
| SCHEMBL826539 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNAEGFRPTGES2KDM4E | |
| SCHEMBL17724636 | 0.80 | TUBB4A (0.67) | ALDH1A1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL19581872 | 0.80 | TUBB4A (0.67) | ALDH1A1LMNATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-1379508-B1 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2010-09-01 | — | — | EP | disclosed |