Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR2C | P28335 | 9/20 | 0.44 |
| ▸ | HRH1 | P35367 | 7/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11219776 | 0.98 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL9442839 | 0.79 | HTR2C (0.41) | SLC6A4SLC6A2HTR2AHTR2C | |
| SCHEMBL11805096 | 0.76 | HTR2C (0.59) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL9442852 | 0.75 | OPRM1 (0.42) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11806534 | 0.74 | HTR2C (0.61) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL11809204 | 0.73 | HTR2C (0.46) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL10633343 | 0.72 | CFTR (0.36) | SLC6A4HTR2AHTR2C | |
| SCHEMBL16356786 | 0.72 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL11042270 | 0.72 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL16356787 | 0.72 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362746-A | Antiviral 1,2,3,4-tetrahydro-1,4-methanonaphthalene derivatives | CANADA PACKERS INC. (CA) | 1982-12-07 | — | — | US | claimed |
| US-4362746-A | Antiviral 1,2,3,4-tetrahydro-1,4-methanonaphthalene derivatives | CANADA PACKERS INC. (CA) | 1982-12-07 | — | — | US | disclosed |