Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | HTR2B | P41595 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633343 | 0.80 | CFTR (0.36) | HTR2CHTR2BHTR2ASLC6A4 | |
| SCHEMBL11805096 | 0.80 | HTR2C (0.59) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL11226929 | 0.79 | SLC6A4 (0.59) | HTR2CHTR2ASLC6A4SLC6A2 | |
| SCHEMBL9442852 | 0.79 | OPRM1 (0.42) | HTR2CHTR2BHTR2ASLC6A4CHRNB4 | |
| Hydrochloric Acid SCHEMBL11806534 | 0.78 | HTR2C (0.61) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL11219776 | 0.78 | SLC6A4 (0.58) | HTR2CHTR2ASLC6A4SLC6A2 | |
| SCHEMBL11809204 | 0.77 | HTR2C (0.46) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL23993626 | 0.74 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4 | |
| SCHEMBL22334896 | 0.74 | HTR2C (0.68) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL21159212 | 0.74 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198567-A | BENZONORBORNENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM | L'OREAL (FR) | 1993-03-30 | — | — | US | disclosed |
| US-5053547-A | BENZONORBORNENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM | L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| US-4931589-A | Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them | L'OREAL (FR) | 1990-06-05 | — | — | US | disclosed |
| US-4810694-A | SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1989-03-07 | — | — | US | disclosed |
| US-4783549-A | Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them | L'OREAL (FR) | 1988-11-08 | — | — | US | disclosed |