SCHEMBL11226971

SCHEMBL11226971

[NH]c1cc(S(=O)(=O)O)ccc1OCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 1/20 0.45
IDO1 P14902 1/20 0.36
TUBB1 Q9H4B7 1/20 0.35
ALDH1A1 P00352 7/20 0.35
GAA P10253 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HSD17B10 Q99714 4/20 0.35
PTGS2 P35354 2/20 0.35
TSHR P16473 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
KDM4E B2RXH2 3/20 0.33
LMNA P02545 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
HPGD P15428 1/20 0.33
NT5E P21589 1/20 0.32
CASR P41180 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9638989 0.82 S1PR3 (0.46) S1PR3ALDH1A1GAAKMT2AMEN1
SCHEMBL11227002 0.81 ALDH1A1 (0.50) S1PR3ALDH1A1GAAKMT2AMEN1
SCHEMBL155352 0.76 POLB (0.48) S1PR3ALDH1A1GAAPOLBHSD17B10
SCHEMBL11804045 0.73 HSD17B10 (0.41) S1PR3ALDH1A1KMT2AMEN1HSD17B10
SCHEMBL9292434 0.72 CA1 (0.49) ALDH1A1GAAHSD17B10TSHRTDP1
SCHEMBL1217133 0.72 ALDH1A1 (0.52) ALDH1A1GAAPOLBMAPTTSHR
SCHEMBL9292547 0.71 CA1 (0.48) ALDH1A1GAAHSD17B10TSHRTDP1
SCHEMBL9293217 0.71 CA1 (0.48) ALDH1A1GAAHSD17B10TSHRTDP1
SCHEMBL9293398 0.71 CA1 (0.48) ALDH1A1GAAHSD17B10TSHRTDP1
SCHEMBL8381611 0.70 ALDH1A1 (0.50) ALDH1A1GAAPOLBMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332938-A Anthaquinone reactive dyestuffs, their preparation and their use for dyeing materials containing OH groups or amide groups BAYER AKTIENGESELLSCHAFT (DE) 1982-06-01 US disclosed
US-4325705-A Anthraquinone reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
EP-0012342-A1 Anthraquinone reactive dyestuffs and their use in dyeing and printing materials that contain hydroxyl groups or amide groups BAYER AG (DE) 1980-06-25 EP disclosed