Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.44 |
| ▸ | HTR2B | P41595 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11030525 | 0.98 | HTR2C (0.43) | HTR2CHTR2BHTR2ATP53GBA1 | |
| SCHEMBL3993920 | 0.79 | OPRL1 (0.43) | — | |
| SCHEMBL10811594 | 0.77 | TP53 (0.43) | HTR2CHTR2BHTR2ATP53 | |
| SCHEMBL927716 | 0.77 | HSD17B3 (0.40) | — | |
| Iodide SCHEMBL1780085 | 0.75 | HSD17B3 (0.39) | — | |
| Iodide SCHEMBL2821259 | 0.75 | HSD17B3 (0.39) | — | |
| Iodide SCHEMBL1780078 | 0.75 | HSD17B3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL30935728 | 0.75 | MEN1 (0.40) | — | |
| SCHEMBL9986948 | 0.72 | OPRM1 (0.43) | HTR2CHTR2BHTR2APARP1ADRB1 | |
| SCHEMBL1780083 | 0.70 | HSD17B3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018417-B1 | NOVEL PIPERIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1982-06-30 | — | — | EP | disclosed |