Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32662848 | 0.97 | RNASEL (0.68) | RNASELADORA1 | |
| SCHEMBL375102 | 0.92 | RNASEL (0.61) | RNASELADORA1 | |
| SCHEMBL23752269 | 0.91 | ADORA1 (0.70) | RNASELADORA1 | |
| SCHEMBL29354292 | 0.89 | P2RY1 (0.77) | RNASELADORA1 | |
| SCHEMBL29389326 | 0.88 | P2RY1 (0.75) | RNASELADORA1 | |
| Adenosine Phosphate SCHEMBL2828289 | 0.87 | P2RY1 (0.76) | RNASELADORA1 | |
| SCHEMBL1526121 | 0.84 | P2RY1 (0.66) | RNASELADORA1 | |
| SCHEMBL29422629 | 0.84 | RNASEL (0.87) | RNASELADORA1 | |
| SCHEMBL905455 | 0.84 | RNASEL (0.87) | RNASELADORA1 | |
| SCHEMBL15807675 | 0.84 | POLB (0.63) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011686-B9 | MODULATION OF HUMAN MAST CELL ACTIVATION | DUSKA SCIENT CO (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-1011686-B1 | MODULATION OF HUMAN MAST CELL ACTIVATION | DUSKA SCIENT CO (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1011686-A4 | MODULATION OF HUMAN MAST CELL ACTIVATION | DUSKA SCIENT CO (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6465441-B2 | Screening method for modulation of human mast cell activation | DUSKA SCIENTIFIC CO. | 2002-10-15 | — | — | US | disclosed |
| US-20020055515-A1 | Screening method for modulation of human mast cell | PLATINUM LONG TERM GROWTH VI, LLC | 2002-05-09 | — | — | US | disclosed |
| US-6372724-B1 | MODULATING HISTAMINE RELEASE; CONTACTING MAST CELLS WITH AGENT WHICH INHIBITS ADENOSINE TRIPHOSPHATE (ATP) FROM BINDING TO P2-PURINOCEPTORS; TREATING ASTHMA AND ALLERGIES | DUSKA SCIENTIFIC CO. | 2002-04-16 | — | — | US | disclosed |
| EP-0929218-A4 | P2Y RECEPTOR ANTAGONISTS | UNIV NORTH CAROLINA (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1011686-A1 | MODULATION OF HUMAN MAST CELL ACTIVATION | Allegheny University of The Health Sciences (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0929218-A2 | P2Y RECEPTOR ANTAGONISTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998042353-A1 | MODULATION OF HUMAN MAST CELL ACTIVATION | ALLEGHENY UNIVERSITY OF THE HEALTH SCIENCES (US) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998018430-A2 | P2Y RECEPTOR ANTAGONISTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-05-07 | — | — | WO | disclosed |