SCHEMBL11227355

SCHEMBL11227355

O=C1CNNC(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17435212 0.74
SCHEMBL1343779 0.73
SCHEMBL17435215 0.72
SCHEMBL11346428 0.72
SCHEMBL427935 0.69
SCHEMBL3497537 0.66
SCHEMBL121542 0.66
SCHEMBL17435216 0.61
SCHEMBL3067298 0.61 CRBN (0.44)
SCHEMBL2216644 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3504214-A1 FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS Novartis AG (CH) 2019-07-03 EP claimed
WO-2018042303-A1 FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS NOVARTIS AG (CH) 2018-03-08 WO claimed
EP-4353718-A4 METHOD FOR PRODUCING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-05 EP disclosed
EP-4353233-A4 PREPARATION CONTAINING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-06-25 EP disclosed
CN-115734965-B Aryltetrahydropyridazine derivatives or salts thereof, and insecticides containing the same and methods of use thereof 日本农药株式会社 2025-05-02 CN disclosed
US-20250115585-A1 METHOD FOR PRODUCING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-10 US disclosed
US-20250115585-A1 METHOD FOR PRODUCING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-10 US disclosed
US-20250011334-A1 FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS NOVARTIS AG (CH) 2025-01-09 US disclosed
CN-118974022-A 1-Aryltetrahydropyridazine-3, 5-dione derivatives or salts thereof, pesticides containing the same, and methods of use thereof 日本农药株式会社 2024-11-15 CN disclosed
CN-118647605-A Mesoionic arylpyridazinium derivatives or salts thereof, pesticides containing the same and methods of use thereof 日本农药株式会社 2024-09-13 CN disclosed
US-20240293402-A1 FORMULATION CONTAINING DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE (as amended) CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-09-05 US disclosed
WO-2016039458-A1 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR 中外製薬株式会社 2016-03-17 WO disclosed
EP-2975030-A1 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 2016-01-20 EP disclosed
EP-2975030-A1 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 2016-01-20 EP disclosed
US-20160002251-A1 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE AND PHARMACEUTICALS CONTAINING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-01-07 US disclosed
US-20160002251-A1 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE AND PHARMACEUTICALS CONTAINING THE SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-01-07 US disclosed
CN-105073715-A Dihydropyridazine-3,5-dione derivative CHUGAI PHARMACEUTICAL CO LTD 2015-11-18 CN disclosed
CN-105073715-A Dihydropyridazine-3,5-dione derivative CHUGAI PHARMACEUTICAL CO LTD 2015-11-18 CN disclosed
WO-2014142273-A1 DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE 中外製薬株式会社 (JP) 2014-09-18 WO disclosed
EP-0019759-B1 N-ARYLTHIOLCARBAMATES, HERBICIDES CONTAINING THEM AND PROCESS FOR COMBATING UNDESIRABLE PLANT GROWTH THEREWITH BASF Aktiengesellschaft (DE) 1982-02-10 EP disclosed