Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236305 | 0.76 | TDP1 (0.37) | — | |
| SCHEMBL11025872 | 0.76 | — | — | |
| SCHEMBL9001174 | 0.75 | TSHR (0.46) | THRBBLMPMP22NPSR1CYP1A2 | |
| SCHEMBL2044917 | 0.74 | ALDH1A1 (0.39) | THRBBLMPMP22NPSR1CYP1A2 | |
| SCHEMBL1424736 | 0.74 | ALDH1A1 (0.39) | THRBBLMPMP22NPSR1CYP1A2 | |
| SCHEMBL5519451 | 0.70 | — | — | |
| SCHEMBL11239819 | 0.70 | THRB (0.35) | THRBBLMPMP22NPSR1CYP1A2 | |
| SCHEMBL29847348 | 0.69 | — | — | |
| SCHEMBL15829742 | 0.69 | TSHR (0.43) | THRBBLMPMP22NPSR1CYP1A2 | |
| SCHEMBL195595 | 0.69 | TSHR (0.43) | THRBBLMPMP22NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358408-A | INSECTICIDES, MITICIDES, NEMATOCIDES | SCHERING AG (DE) | 1982-11-09 | — | — | US | disclosed |