Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123593 | 0.91 | NR4A1 (0.48) | NR4A1NR4A2NR4A3F10KMT2A | |
| SCHEMBL1123052 | 0.90 | NR4A1 (0.45) | NR4A1NR4A2NR4A3F10KMT2A | |
| SCHEMBL1123189 | 0.88 | LPAR1 (0.51) | F10KMT2AKDM4EALDH1A1LPAR1 | |
| SCHEMBL1122983 | 0.87 | NR4A1 (0.46) | NR4A1NR4A2NR4A3F10KMT2A | |
| SCHEMBL1123277 | 0.85 | PPARG (0.49) | F10KMT2AKDM4EALDH1A1LPAR1 | |
| SCHEMBL1122914 | 0.85 | KMT2A (0.51) | NR4A2F10KMT2ASLC2A1PPARG | |
| SCHEMBL1123181 | 0.79 | LPAR1 (0.49) | F10KMT2ALPAR1SLC2A1PPARG | |
| SCHEMBL1123395 | 0.79 | F10 (0.51) | NR4A2F10KMT2ALPAR1PPARG | |
| SCHEMBL1123247 | 0.78 | SLC2A1 (0.47) | F10KMT2ALPAR1SLC2A1PPARG | |
| SCHEMBL1122837 | 0.78 | PPARG (0.51) | KMT2AKDM4EALDH1A1LPAR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |