Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123181 | 0.90 | LPAR1 (0.49) | F10MAPTLTA4HESR1KMT2A | |
| SCHEMBL1122783 | 0.90 | NR4A1 (0.49) | NR4A1NR4A2NR4A3F10MAPT | |
| SCHEMBL1122636 | 0.88 | BCHE (0.50) | NR4A2KMT2ASMN1; SMN2MAOBRAB9A | |
| SCHEMBL1123324 | 0.88 | LPAR1 (0.46) | F10ESR1KMT2ALPAR1KDM4E | |
| SCHEMBL1123593 | 0.85 | NR4A1 (0.48) | NR4A1NR4A2NR4A3F10MAPT | |
| SCHEMBL1122983 | 0.85 | NR4A1 (0.46) | NR4A1NR4A2NR4A3F10MAPT | |
| SCHEMBL1123230 | 0.81 | LPAR1 (0.48) | LTA4HLPAR1MAOBSLC2A1NPC1 | |
| SCHEMBL1122799 | 0.81 | L3MBTL1 (0.53) | MAPTLTA4HKMT2ALPAR1ALDH1A1 | |
| SCHEMBL1123467 | 0.79 | NPC1 (0.55) | NR4A2MAPTTP53KMT2ASMN1; SMN2 | |
| SCHEMBL1123189 | 0.78 | LPAR1 (0.51) | F10KMT2ALPAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |