Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 6/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123277 | 0.92 | PPARG (0.49) | KMT2APTGESPPARGPPARAALOX5 | |
| SCHEMBL1123557 | 0.91 | PTGES (0.52) | KMT2ABCHEPTGESNR4A2MAOB | |
| SCHEMBL1123174 | 0.89 | NR4A2 (0.59) | KMT2ABCHEPTGESNR4A2MAOB | |
| SCHEMBL1123189 | 0.89 | LPAR1 (0.51) | KMT2AMAOBPPARGPPARASLC2A1 | |
| SCHEMBL1122636 | 0.89 | BCHE (0.50) | KMT2ABCHEPTGESNR4A2MAOB | |
| SCHEMBL1123406 | 0.87 | NR4A2 (0.56) | KMT2APTGESNR4A2MAOBALOX5 | |
| SCHEMBL1123118 | 0.86 | KMT2A (0.58) | KMT2APTGESNR4A2MAOBSMPD1 | |
| SCHEMBL1123250 | 0.86 | L3MBTL1 (0.53) | BCHEPTGESNR4A2MAOBPPARG | |
| SCHEMBL1123394 | 0.86 | KMT2A (0.52) | KMT2APTGESNR4A2MAOBPPARG | |
| SCHEMBL1122783 | 0.85 | NR4A1 (0.49) | KMT2ANR4A2MAOBPPARGSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |