Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 4/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024349 | 1.00 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL4410810 | 0.87 | SLC7A5 (0.66) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL1003560 | 0.85 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL5699042 | 0.85 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL5608077 | 0.85 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL10460552 | 0.85 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL9117821 | 0.85 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL10460553 | 0.85 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7623712 | 0.85 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL29682444 | 0.85 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317770-A | WITH IMPROVED IN-VIVO ANAGESIC ACTIVITY | HOFFMANN-LA ROCHE INC. (US) | 1982-03-02 | — | — | US | disclosed |