Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.62 |
| ▸ | GPR34 | Q9UPC5 | 7/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936629 | 0.91 | PTPN1 (0.58) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123459 | 0.91 | GAA (0.67) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123300 | 0.91 | GPR132 (0.59) | GPR132GPR34PTPN1PPARG | |
| SCHEMBL1123310 | 0.89 | PTPN1 (0.61) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123232 | 0.88 | GPR132 (0.77) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL27658914 | 0.88 | GPR132 (0.77) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123299 | 0.88 | GPR132 (0.77) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123033 | 0.88 | GPR132 (0.77) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1123267 | 0.88 | GPR132 (0.62) | GPR132GPR34PTPN1PPARGGAA | |
| SCHEMBL1122757 | 0.87 | GPR132 (0.78) | GPR132GPR34PTPN1PPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |