SCHEMBL11228066

SCHEMBL11228066

O=C(CCN1CCCCC1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
KMT2A Q03164 6/20 0.60
HPGD P15428 3/20 0.60
MAOB P27338 1/20 0.60
MAPT P10636 4/20 0.59
HSD17B10 Q99714 2/20 0.59
GFER P55789 1/20 0.59
SIGMAR1 Q99720 1/20 0.58
MEN1 O00255 2/20 0.57
KDM4E B2RXH2 1/20 0.57
GAA P10253 1/20 0.57
MAPK1 P28482 1/20 0.57
ATM Q13315 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 3/20 0.56
HTT P42858 2/20 0.56
POLB P06746 1/20 0.56
TP53 P04637 2/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7929078 0.91 SIGMAR1 (0.61) ALDH1A1KMT2AHPGDMAOBMAPT
SCHEMBL12123774 0.85 ALDH1A1 (0.72) ALDH1A1KMT2AHPGDMAPTSIGMAR1
Hydrochloric Acid SCHEMBL7932162 0.85 SIGMAR1 (0.56) ALDH1A1KMT2AHPGDMAPTHSD17B10
Hydrochloric Acid SCHEMBL7932172 0.84 ALDH1A1 (0.70) ALDH1A1KMT2AHPGDMAPTSIGMAR1
SCHEMBL17033397 0.83 ALDH1A1 (0.72) ALDH1A1KMT2AHPGDMAPTHSD17B10
SCHEMBL26922539 0.83 ALDH1A1 (0.68) ALDH1A1KMT2AHPGDMAOBMAPT
SCHEMBL11636967 0.83 ALDH1A1 (0.52) ALDH1A1KMT2AHPGDMAOBMAPT
Hydrochloric Acid SCHEMBL9318230 0.82 ALDH1A1 (0.53) ALDH1A1KMT2AHPGDMAOBMAPT
Hydrochloric Acid SCHEMBL5954595 0.81 ALDH1A1 (0.71) ALDH1A1KMT2AHPGDMAPTHSD17B10
Hydrochloric Acid SCHEMBL5358799 0.81 HTT (0.61) ALDH1A1KMT2AGFERSIGMAR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4333941-A Inhibition of enveloped viruses with phenyl ketones THE DOW CHEMICAL COMPANY (US) 1982-06-08 US claimed
US-4333941-A Inhibition of enveloped viruses with phenyl ketones THE DOW CHEMICAL COMPANY (US) 1982-06-08 US disclosed