Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837846 | 0.94 | POLB (0.50) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL29657635 | 0.93 | POLB (0.49) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL12394952 | 0.91 | POLB (0.47) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL4066747 | 0.91 | POLB (0.47) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL12394951 | 0.91 | POLB (0.47) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL14262508 | 0.90 | TDP1 (0.49) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL14262501 | 0.90 | POLB (0.49) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL345789 | 0.89 | TDP1 (0.61) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL19320454 | 0.89 | POLB (0.48) | TDP1POLBAPEX1HTTMEN1 | |
| SCHEMBL5164883 | 0.86 | POLB (0.44) | TDP1POLBAPEX1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57038750-A | — | — | None | — | — | JP | disclosed |
| JP-S5738750-A | 2,3-BIS 3,4-DICARBOXYBENZOYLOXY PROPYL METHACRYLATE AND ITS PREPARATION | KURARAY CO LTD | 1982-03-03 | — | — | JP | disclosed |