Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657635 | 0.99 | POLB (0.49) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL4066747 | 0.96 | POLB (0.47) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL12394952 | 0.96 | POLB (0.47) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL12394951 | 0.96 | POLB (0.47) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL14262501 | 0.96 | POLB (0.49) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL14262508 | 0.96 | TDP1 (0.49) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL19320454 | 0.94 | POLB (0.48) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL11228078 | 0.94 | TDP1 (0.54) | POLBTDP1APEX1HTTCDC25A | |
| SCHEMBL544688 | 0.90 | TDP1 (0.56) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL543628 | 0.90 | POLB (0.56) | POLBTDP1APEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648394-B2 | Methods of implanting a device into a brain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-16 | — | — | US | claimed |
| EP-1346717-B1 | One-bottle dental bonding composition | DENTSPLY SANKIN K K (JP) | 2007-05-23 | — | — | EP | claimed |
| US-20030187092-A1 | One-bottle dental bonding composition | DENTSPLY-SANKIN K.K. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1346717-A1 | One-bottle dental bonding composition | DENTSPLY-SANKIN K.K. (JP) | 2003-09-24 | — | — | EP | claimed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | claimed |
| US-5091441-A | DENTAL COMPOSITION | KURARAY CO., LTD. (JP) | 1992-02-25 | — | — | US | claimed |
| JP-62230709-A | — | — | None | — | — | JP | disclosed |
| US-12441821-B2 | (Meth)acrylate and use thereof | MITSUI CHEMICALS, INC. (JP) | 2025-10-14 | — | — | US | disclosed |
| US-20250122315-A1 | (METH)ACRYLATE AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2025-04-17 | — | — | US | disclosed |
| US-12168123-B2 | Methods of implanting a device into a brain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-17 | — | — | US | disclosed |
| EP-3603606-B1 | ADHESIVE MONOMER FOR DENTAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2024-11-13 | — | — | EP | disclosed |
| EP-3719043-B1 | (METH)ACRYLATE, MONOMER COMPOSITION, DENTAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PRODUCTION METHOD THEREOF | MITSUI CHEMICALS INC (JP) | 2024-11-13 | — | — | EP | disclosed |
| US-20240173211-A1 | DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT | SHOFU INC. (JP) | 2024-05-30 | — | — | US | disclosed |
| EP-0323521-A1 | CURABLE COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |
| EP-0282280-A1 | Curable adhesive compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0277413-A2 | Adhesive particularly for dental use | KURARAY CO., LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |
| EP-0266220-A2 | Curable composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-05-04 | — | — | EP | disclosed |
| JP-S62230709-A | PHOTO-CURABLE SURFACE-TREATING AGENT AND ADHESIVE SURFACE FOR DENTAL USE | MITSUI PETROCHEM IND LTD | 1987-10-09 | — | — | JP | disclosed |
| US-4548689-A | RADICAL POLYMERIZABLE MONOMER, KETOCARBONYL COMPOUND AND MERCAPTOB | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0136186-A2 | Photocurable resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122315-A1 | (METH)ACRYLATE AND USE THEREOF | TST, MMAB, BHMT2 | POLB 2615/4885TDP1 1505/4885APEX1 374/4885 |
| US-12441821-B2 | (Meth)acrylate and use thereof | TST, MMAB, BHMT2 | POLB 2615/4885TDP1 1505/4885APEX1 374/4885 |
| US-20240173211-A1 | DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT | GRIK1, GRIN2B, GRIK2 | POLB 1327/4885TDP1 4237/4885APEX1 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.