SCHEMBL4066747

SCHEMBL4066747

C=C(C)C(=O)OCCOCCOCCOCCOC(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
THRB P10828 1/20 0.45
SERPINE1 P05121 2/20 0.40
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ABCB11 O95342 1/20 0.36
CYP3A4 P08684 1/20 0.36
ADRA2B P18089 1/20 0.36
OPRD1 P41143 1/20 0.36
SCN5A Q14524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394952 1.00 POLB (0.47) POLBTDP1APEX1HTTTHRB
SCHEMBL12394951 1.00 POLB (0.47) POLBTDP1APEX1HTTTHRB
SCHEMBL837846 0.96 POLB (0.50) POLBTDP1APEX1HTTTHRB
SCHEMBL29657635 0.95 POLB (0.49) POLBTDP1APEX1HTTTHRB
SCHEMBL14262508 0.92 TDP1 (0.49) POLBTDP1APEX1HTTTHRB
SCHEMBL14262501 0.92 POLB (0.49) POLBTDP1APEX1HTTTHRB
SCHEMBL2787758 0.91 POLB (0.52) POLBTDP1APEX1HTTTHRB
SCHEMBL19320454 0.91 POLB (0.48) POLBTDP1APEX1HTTTHRB
SCHEMBL11228078 0.91 TDP1 (0.54) POLBTDP1APEX1HTTSERPINE1
SCHEMBL17800992 0.87 POLB (0.51) POLBTDP1APEX1HTTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140224140-A1 PRINTING METHOD USING LITHOGRAPHIC PRINTING PLATE PRECURSOR OF ON-PRESS DEVELOPMENT TYPE FUJIFILM COPORATION (JP) 2014-08-14 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20120227605-A1 ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT FUJIFILM CORPORATION (JP) 2012-09-13 US disclosed
US-20120103220-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR SONOKAWA KOJI (JP) 2012-05-03 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
US-20110134411-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING METHOD AND PACKAGED BODY OF LITHOGRAPHIC PRINTING PLATE PRECURSORS MITSUMOTO TOMOYOSHI 2011-06-09 US disclosed
US-7939240-B2 Lithographic printing plate precursor and method of producing printing plate FUJIFILM CORPORATION (JP) 2011-05-10 US disclosed
US-20110091814-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS OOHASHI HIDEKAZU 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054212-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS FLNA, PFN1, FLNB POLB 1208/4885TDP1 1843/4885APEX1 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.