Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27328 | 0.87 | IDO1 (0.58) | GSK3BIDO1CMA1CA12CA1 | |
| SCHEMBL1405603 | 0.82 | CA1 (0.65) | PTGS2GSK3BMAPTMEN1KMT2A | |
| SCHEMBL1405602 | 0.82 | CA1 (0.65) | PTGS2GSK3BMAPTMEN1KMT2A | |
| SCHEMBL16454927 | 0.82 | PTGS2 (0.50) | PTGS2MAPTIDO1PPARDPPARA | |
| SCHEMBL21633729 | 0.81 | MAOB (0.59) | IDO1CMA1CA12CA1CA2 | |
| SCHEMBL11767489 | 0.80 | PTGS2 (0.49) | PTGS2MAPTIDO1PPARDPPARA | |
| SCHEMBL11768791 | 0.80 | PTGS2 (0.49) | PTGS2MAPTIDO1PPARDPPARA | |
| SCHEMBL11767492 | 0.80 | PTGS2 (0.49) | PTGS2MAPTIDO1PPARDPPARA | |
| SCHEMBL11228128 | 0.80 | PTGS2 (0.49) | PTGS2MAPTIDO1PPARDPPARA | |
| SCHEMBL1456261 | 0.77 | PTGS2 (0.46) | PTGS2GSK3BMAPTIDO1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000252-B1 | PEPTIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE PEPTIDES AND A PROCESS FOR THE PREPARATION OF THE PEPTIDES | BEECHAM GROUP PLC (GB) | 1982-02-03 | — | — | EP | disclosed |