SCHEMBL21633729

SCHEMBL21633729

COc1ccc(-c2ccc(C[O])cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.59
IDO1 P14902 3/20 0.52
ESR2 Q92731 1/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CMA1 P23946 1/20 0.48
AGXT P21549 2/20 0.48
LTA4H P09960 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
APP P05067 2/20 0.47
HTT P42858 1/20 0.47
LDHA P00338 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27328 0.93 IDO1 (0.58) IDO1CA12CA1CA2CA7
SCHEMBL24093424 0.82 MAOB (0.59) MAOBIDO1ESR2CA12CA1
SCHEMBL6059611 0.81 LTA4H (0.71) MAOBIDO1ESR2CA12CA1
SCHEMBL22451382 0.81 LTA4H (0.71) MAOBIDO1ESR2CA12CA1
SCHEMBL11228126 0.81 PTGS2 (0.53) IDO1CA12CA1CA2CA7
SCHEMBL197522 0.80 CA1 (0.79) MAOBESR2CA12CA1CA2
SCHEMBL9151672 0.80 CA1 (0.79) MAOBESR2CA12CA1CA2
SCHEMBL6733562 0.80 CA1 (0.79) MAOBESR2CA12CA1CA2
SCHEMBL1623907 0.79 MAOB (0.61) MAOBIDO1ESR2CA12CA1
SCHEMBL17614860 0.79 MAOB (0.61) MAOBIDO1ESR2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339565-B Photochromic compound and composition 光学转变公司 2018-08-14 CN claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111315828-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-06-19 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
CN-103339565-B Photochromic compound and composition 光学转变公司 2018-08-14 CN disclosed
CN-104755970-B The photochromic article of photochromic dichroism and fixed polarizing layer with least part cross polarization 光学转变公司 2018-01-16 CN disclosed
CN-105142875-B The method for preparing the photochromic dichroism film with the optical distortion for reducing 光学转变公司 2017-07-07 CN disclosed