Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050838 | 0.81 | CYP3A4 (0.63) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL28902793 | 0.80 | SMN1; SMN2 (0.53) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL25346861 | 0.80 | CYP3A4 (0.53) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL21091712 | 0.78 | ALDH1A1 (0.50) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL30829749 | 0.77 | LMNA (0.58) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL11718702 | 0.77 | LMNA (0.58) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL6234259 | 0.77 | LMNA (0.61) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL10966109 | 0.77 | CYP3A4 (0.61) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL19783655 | 0.76 | ALDH1A1 (0.49) | LMNAPDE10ACYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL934808 | 0.76 | PSMB8 (0.56) | LMNATDP1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039809-A2 | 2-Amino-5-halogen-benzothiazoles, process for preparing them and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | claimed |
| EP-0039809-A3 | 2-AMINO-5-HALOGEN-BENZOTHIAZOLES, PROCESS FOR PREPARING THEM AND MEDICINES CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0039809-A2 | 2-Amino-5-halogen-benzothiazoles, process for preparing them and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039809-A2 | 2-Amino-5-halogen-benzothiazoles, process for preparing them and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |