SCHEMBL11228176

SCHEMBL11228176

O=C(CS)OC(=O)OC(=O)CS

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL407915 0.86
SCHEMBL11801096 0.78
SCHEMBL10630073 0.78 TSHR (0.48) TSHRHSD17B10ALDH1A1
SCHEMBL2324008 0.75
SCHEMBL11856859 0.73 TSHR (0.43) TSHRHSD17B10
SCHEMBL8370998 0.73 TSHR (0.43) TSHRHSD17B10
SCHEMBL3226093 0.73 ALDH1A1 (0.43) TSHRHSD17B10ALDH1A1
SCHEMBL6270090 0.72 TSHR (0.56) TSHRHSD17B10
SCHEMBL10414527 0.71
SCHEMBL561885 0.69 TSHR (0.40) TSHRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 US disclosed