Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248963 | 0.87 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPK1KDM4ENPC1 | |
| SCHEMBL11249067 | 0.85 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPK1KDM4ENPC1 | |
| SCHEMBL11236198 | 0.83 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPK1KDM4ENPC1 | |
| SCHEMBL11240925 | 0.82 | SLC22A12 (0.46) | MAPK1KDM4EMCL1SLC22A12OGG1 | |
| SCHEMBL11242199 | 0.82 | SMN1; SMN2 (0.54) | L3MBTL1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11235501 | 0.81 | MAPT (0.49) | L3MBTL1ALDH1A1MAPK1NPC1RAB9A | |
| Methane SCHEMBL11238637 | 0.81 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11237145 | 0.78 | NPC1 (0.47) | L3MBTL1ALDH1A1NPC1RAB9APKM | |
| SCHEMBL11423074 | 0.77 | TTR (0.43) | L3MBTL1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11240749 | 0.77 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPK1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334078-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATICS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-08 | — | — | US | disclosed |
| US-4219657-A | USED AS ANTIINFLAMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-08-26 | — | — | US | disclosed |