Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122939 | 0.81 | KMT2A (0.45) | LMNATP53KMT2AMEN1ADRB2 | |
| SCHEMBL1122756 | 0.78 | KMT2A (0.55) | KMT2AMEN1ADRB2NPC1RAB9A | |
| SCHEMBL5720725 | 0.77 | KMT2A (0.42) | LMNATP53KMT2AMEN1ADRB2 | |
| SCHEMBL1122685 | 0.72 | F10 (0.38) | LMNATP53KMT2AMEN1TSHR | |
| SCHEMBL1123197 | 0.72 | MEN1 (0.43) | KMT2AMEN1ADRB2NPC1HPGD | |
| SCHEMBL6703333 | 0.67 | KMT2A (0.53) | TP53KMT2AMEN1NPC1HPGD | |
| SCHEMBL9402627 | 0.65 | SMPD1 (0.62) | LMNATP53KMT2ATSHRSMPD1 | |
| SCHEMBL9402734 | 0.65 | SMPD1 (0.62) | LMNATP53KMT2ATSHRSMPD1 | |
| SCHEMBL9402732 | 0.65 | SMPD1 (0.62) | LMNATP53KMT2ATSHRSMPD1 | |
| SCHEMBL2452841 | 0.65 | HSD17B2 (0.54) | LMNATP53NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |