SCHEMBL1122685

SCHEMBL1122685

O=C(O)CN(Cc1ccsc1)C(=O)c1cccc(OCCSc2cccs2)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
F2 P00734 1/20 0.36
SLC2A1 P11166 3/20 0.36
PPARA Q07869 5/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
KMT2A Q03164 1/20 0.35
PPARG P37231 5/20 0.35
TSHR P16473 2/20 0.35
FFAR1 O14842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122756 0.77 KMT2A (0.55) MEN1KMT2A
SCHEMBL5720725 0.74 KMT2A (0.42) LMNATP53F2MEN1KMT2A
SCHEMBL1122848 0.72 LMNA (0.46) F10LMNATP53MEN1KMT2A
SCHEMBL1122939 0.72 KMT2A (0.45) LMNATP53MEN1KMT2APPARG
SCHEMBL1123174 0.69 NR4A2 (0.59) LMNASLC2A1PPARAKMT2AFFAR1
SCHEMBL1123197 0.67 MEN1 (0.43) MEN1KMT2APPARG
SCHEMBL1123406 0.67 NR4A2 (0.56) LMNASLC2A1KMT2ATSHRFFAR1
SCHEMBL1122914 0.67 KMT2A (0.51) F10SLC2A1PPARAKMT2APPARG
SCHEMBL1123277 0.67 PPARG (0.49) F10SLC2A1PPARAMEN1KMT2A
SCHEMBL1123189 0.66 LPAR1 (0.51) F10SLC2A1PPARAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1644321-B1 NEW BENZAMIDES AS PPATY MODULATORS S A L V A T LAB SA (ES) 2011-02-09 EP disclosed
US-20060160894-A1 Benzamides as ppar modulators LABORATORIOS S.A.L.V.A.T.,S.A. (ES) 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060160894-A1 Benzamides as ppar modulators PPARD, PPARA, PPARG F10 4518/4885LMNA 1251/4885TP53 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.