Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | GRK3 | P35626 | 2/20 | 0.48 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xibenolol SCHEMBL79880 | 0.88 | CYP2D6 (0.70) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| Xibenolol SCHEMBL6506961 | 0.88 | CYP2D6 (0.70) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| Xibenolol SCHEMBL29387811 | 0.88 | CYP2D6 (0.70) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| Xibenolol SCHEMBL79879 | 0.88 | CYP2D6 (0.70) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| Xibenolol SCHEMBL7267198 | 0.86 | CYP2D6 (0.72) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL11855803 | 0.81 | CASR (0.70) | CYP2D6MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL3956865 | 0.80 | ALOX15 (0.63) | CYP2D6KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL11223419 | 0.78 | ADRB2 (0.62) | CYP2D6MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10893056 | 0.78 | GRK3 (0.49) | CYP2D6MAPTKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9506677 | 0.78 | KMT2A (0.50) | CYP2D6KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |