SCHEMBL11228625

SCHEMBL11228625

CC1(C)CC(=O)N(c2cccc(NO)c2)C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.48
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
GRM4 Q14833 1/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PARP1 P09874 1/20 0.36
PARP15 Q460N3 1/20 0.36
PARP10 Q53GL7 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10853443 0.82 RAB9A (0.48) ARKMT2AMEN1GRM4ALDH1A1
SCHEMBL10850328 0.79 AR (0.48) ARKMT2AMEN1GRM4ALDH1A1
SCHEMBL2510494 0.79 AR (0.52) ARKMT2AMEN1ALDH1A1KDM4E
SCHEMBL13689506 0.78 AR (0.51) ARKMT2AMEN1GRM4ALDH1A1
SCHEMBL2275042 0.78 ALDH1A1 (0.59) ARKMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL10857073 0.76 MEN1 (0.43) ARKMT2AMEN1GRM4ALDH1A1
SCHEMBL10855612 0.76 ALDH1A1 (0.51) ARKMT2AMEN1ALDH1A1HPGD
SCHEMBL1935538 0.75 HPN (0.59) ARKMT2AMEN1ALDH1A1LMNA
SCHEMBL11194375 0.72 AR (0.46) ARKMT2AMEN1GRM4ALDH1A1
SCHEMBL9637492 0.70 AR (0.52) ARKMT2AALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4400202-A N-m-Phenyl glutarimide derivatives and their use as herbicides STAUFFER CHEMICAL COMPANY (US) 1983-08-23 US disclosed