Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628512 | 0.75 | HRH2 (0.38) | HRH2HRH1HRH4HRH3TDP1 | |
| Hydrochloric Acid SCHEMBL10458812 | 0.74 | TDP1 (0.40) | HRH2HRH1HRH4HRH3TDP1 | |
| Hydrochloric Acid SCHEMBL10458810 | 0.74 | TDP1 (0.40) | HRH2HRH1HRH4HRH3TDP1 | |
| Bromide SCHEMBL11679779 | 0.74 | HRH2 (0.37) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL11353887 | 0.71 | HRH2 (0.31) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL3669928 | 0.69 | HRH2 (0.33) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL2627829 | 0.68 | — | — | |
| SCHEMBL3666541 | 0.67 | HRH2 (0.31) | HRH2HRH1HRH4HRH3TDP1 | |
| Hydrochloric Acid SCHEMBL28608493 | 0.67 | L3MBTL1 (0.45) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL12342223 | 0.66 | HRH2 (0.38) | HRH2HRH1HRH4HRH3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322539-A | BY REACTION WITH AMINOALKYLENE THIOLS | ETHYL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | disclosed |